Concepedia

Haploidentical stem cell transplant with post-transplantation cyclophosphamide and mini-dose methotrexate in children

Diego Medina, Mayra Estacio, María Rosales, Eliana Manzi

Hematology/Oncology and Stem Cell Therapy · 2020 · 19 citations · 23 references

DOIFull text

Open access

Abstract

Haplo-SCT with PT/Cy can be an available, safe, and feasible option for children with hematologic malignancies; meanwhile, the use of mini-dose of MTX was associated with lower rates of acute GVHD. However, our results require further support from prospective randomized studies to improve the efficacy of this prophylactic strategy.

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