<p>Sex Differences in Associations Between CYP2D6 Phenotypes and Response to Opioid Analgesics</p>

Abstract

We replicated and extended the findings of previous research indicating associations between CYP2D6 phenotypes and response to opioids. In addition, the observed associations were stronger in women than in men. We recommend sex differences to be factored in future research investigating associations between pharmacogenomics and response to medications.