Origins and clonal convergence of gastrointestinal IgE <sup>+</sup> B cells in human peanut allergy

Ramona A. Hoh, Shilpa A. Joshi, Ji-Yeun Lee, Brock A. Martin, Sushama Varma, Shirley Kwok, Sandra C. A. Nielsen, Parastu Nejad, Emily Haraguchi, Priya S. Dixit,

Science Immunology · 2020 · 133 citations · 40 references

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Abstract

Peanut-allergic patient GI tissues implicate local IgE class-switching and common IgH genetic rearrangements in pathogenesis.

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