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Development and characterization of a novel anti-OX40 antibody for potent immune activation

Zhihui Kuang, Jing Hua, Zhihai Wu, Jie Wang, Yiming Li, Haiqing Ni, Pan Zhang, Weiwei Wu, Min Wu, Shuaixiang Zhou,

Cancer Immunology Immunotherapy · 2020 · 30 citations · 15 references

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References

15

OX40 Is a Potent Immune-Stimulating Target in Late-Stage Cancer Patients

Brendan D. Curti, Magdalena Kovacsovics-Bankowski, Nicholas P. Morris et al. · Cancer Research · 2013 · 509 citations

, , +15

OX40 costimulation turns off Foxp3+ Tregs

Minh Diem Vu, Xiang Xiao, Wenda Gao et al. · Blood · 2007 · 418 citations · Full text

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Depleting tumor-specific Tregs at a single site eradicates disseminated tumors

Aurélien Marabelle, Holbrook E. Kohrt, Idit Sagiv-Barfi et al. · Journal of Clinical Investigation · 2013 · 405 citations · Full text

, , +17

Depleting tumor-specific Tregs at a single site eradicates disseminated tumors

Aurélien Marabelle, Holbrook E. Kohrt, Idit Sagiv-Barfi et al. · Journal of Clinical Investigation · 2013 · 309 citations · Full text

, , +17

OX40 engagement depletes intratumoral Tregs via activating FcγRs, leading to antitumor efficacy

Yannick Bulliard, Rose Jolicoeur, Jimin Zhang et al. · Immunology and Cell Biology · 2014 · 291 citations

, , +17