The role of the CDCA gene family in ovarian cancer

Abstract

Up-regulated <i>CDCA</i> gene expression in ovarian cancer tissues probably played a crucial part in the occurrence of ovarian cancer. The up-regulated <i>CDCA2/3/5/7</i> expression levels were used as the potential prognostic markers to improve the poor ovarian cancer survival and prognostic accuracy. Moreover, <i>CDCA</i> genes probably exerted their functions in tumorigenesis through the PLK1 pathway.