PubMed · 2019 · 18 citations · 0 references
MedicineGynecologyPathologyCervical DiseaseCytopathologyGynecologic OncologyCervical CancerCervical CytologyCervical LesionsCervical PathologyGynecologic CytologyGynecologic PathologyCervical Intraepithelial Neoplasia DiagnosisCervical Pathology AssessmentCervical Squamous LesionsColposcopic Cervical BiopsyHigh-grade Squamous Intraepithelial Lesion DetectionMenopausal StatusSquamous Intraepithelial Lesion AssessmentTreatment Modality Selection
(1) The lesions of HSIL in post-menopausal patients still have definite features under colposcopy as same as pre-menopausal patients. Endocervical curettage could help detect more HSIL in post-menopausal patients. Compared with pre-menopausal patients, post-menopausal HSIL patients have an increased risk of cervical cancer and are more likely missed by cervical tissue sampling. (2) LEEP has the dual effects of diagnosis and treatment, and is still the recommended treatment for post-menopausal HSIL patients. However, the increase in positive rate of endocervical margin and residual rate requires further active intervention. (3) Considering those post-menopausal HSIL patients who cannot accept conization as the initial treatment, the selection of hysterectomy type requires more thorough study.