DNA-methylation-mediated activating of lncRNA SNHG12 promotes temozolomide resistance in glioblastoma

Radiotherapy plus Concomitant and Adjuvant Temozolomide for Glioblastoma

Roger Stupp, Warren Mason, Martin J. van den Bent et al. · New England Journal of Medicine · 2005 · 21K citations · Full text

A ceRNA Hypothesis: The Rosetta Stone of a Hidden RNA Language?

Leonardo Salmena, Laura Poliseno, Yvonne Tay et al. · Cell · 2011 · 7.6K citations · Full text

Functional Genomics, Engineering, Genetics +12

A restricted cell population propagates glioblastoma growth after chemotherapy

Jian Chen, Yanjiao Li, Tzong‐Shiue Yu et al. · Nature · 2012 · 2.3K citations

Neuro-oncology, Tumor Heterogeneity, Cell Population +8

m 6 A Demethylase ALKBH5 Maintains Tumorigenicity of Glioblastoma Stem-like Cells by Sustaining FOXM1 Expression and Cell Proliferation Program

Sicong Zhang, Boxuan Zhao, Aidong Zhou et al. · Cancer Cell · 2017 · 1.5K citations · Full text

Tumor Biology, Glioma, Medicine +12

Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer

Yeshayahu Schlesinger, Ravid Straussman, Ilana Keshet et al. · Nature Genetics · 2006 · 1.2K citations

Histone Modifications, Chromatin, Polycomb-mediated Methylation +12