The ratio of plasma angiopoietin-2 to angiopoietin-1 as a prognostic biomarker in patients with sepsis

The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)

Mervyn Singer, Clifford S. Deutschman, Christopher W. Seymour et al. · JAMA · 2016 · 28K citations · Full text

Veterinary Medicine, Immunology, Pathobiology +17

Angiopoietin-2, a Natural Antagonist for Tie2 That Disrupts in vivo Angiogenesis

Peter C. Maisonpierre, Chitra Suri, Pamela F. Jones et al. · Science · 1997 · 3.6K citations

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The inducing role of tumor necrosis factor in the development of bactericidal granulomas during BCG infection

Vincent Kindler, André‐Pascal Sappino, Georges E. Grau et al. · Cell · 1989 · 1.3K citations

Life Sciences, Immunology, Microbiology +17

Angiopoietin-1 and angiopoietin-2 as clinically informative prognostic biomarkers of morbidity and mortality in severe sepsis*

Daniel Ricciuto, Claúdia C. dos Santos, Michael Hawkes et al. · Critical Care Medicine · 2011 · 238 citations

Veterinary Medicine, Internal Medicine, Acute Care Medicine +16

Angiopoietin-2 is increased in severe sepsis: Correlation with inflammatory mediators

Stylianos E. Orfanos, Constantinos Glynos, Chariclea Athanasiou et al. · Critical Care Medicine · 2006 · 213 citations

Veterinary Medicine, Immunology, Pathobiology +16