Low preoperative serum ALB level is independently associated with poor overall survival in endometrial cancer patients

Abstract

<b>Aim:</b> To reveal the prognostic significance of serum albumin (ALB) concentration in endometrial cancer (EC) patients in China. <b>Patients & methods:</b> 345 EC patients were enrolled in a single center, and the preoperative serum ALB concentration were measured. Kaplan-Meier curve analysis and Cox proportional hazards regression model were performed to evaluate the associations between ALB concentration and overall survival (OS) of EC patients. <b>Results:</b> The EC patients with lower preoperative serum ALB concentration exhibited a significantly poorer OS (p < 0.05). Univariate analysis and multivariate analysis indicated that serum ALB concentration was an independent prognostic factor of unfavorable OS for EC patients. <b>Conclusion:</b> Our results showing that ALB concentration may serve as an independent prognostic factor for EC patients.