Frequency of Thrombocytopenia and Heparin-Induced Thrombocytopenia in Patients Receiving Extracorporeal Membrane Oxygenation Compared With Cardiopulmonary Bypass and the Limited Sensitivity of Pretest Probability Score

Deepa J. Arachchillage, Sanjay Khanna, Christophe Vandenbriele, Farah Kamani, Maurizio Passariello, Alex Rosenberg, TC Aw, Winston Banya, Stéphane Ledot, Brijesh Patel

Critical Care Medicine · 2020 · 27 citations · 26 references

Abstract

Thrombocytopenia is already common at extracorporeal membrane oxygenation initiation. Heparin-induced thrombocytopenia is more frequent in both venovenous- and venoarterial-extracorporeal membrane oxygenation compared with cardiopulmonary bypass. Positive predictive value of Pretest Probability Score in identifying heparin-induced thrombocytopenia was lower in extracorporeal membrane oxygenation patients. Heparin-induced thrombocytopenia had no effect on mortality.

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