<p>P53 Mutant p53<sup>N236S</sup> Regulates Cancer-Associated Fibroblasts Properties Through Stat3 Pathway</p>

Abstract

Our results illustrate that p53S plays an important role in CAFs activation by the Stat3 pathway. The study indicates that cancer cells and fibroblasts interaction promotes prostate cancer cell growth, migration and invasion due to p53S expression in fibroblasts.