The Pediatric Infectious Disease Journal · 2020 · 11 citations · 2 references
PharmacyInfectious DiseasesPharmacotherapyAntimicrobial PharmacotherapyAntimicrobial ResistancePediatric Infectious DiseasesAntibacterial PharmacotherapyAntibacterial TherapyAntibiotic ResistanceCombination Antimicrobial TherapyPediatric Antibiotic TherapyPediatric Antimicrobial TherapyAdverse Drug EventsMicrobiological CurePatient Dose ReductionPediatric Infection TreatmentPseudomonas Aeruginosa Infection TreatmentPseudomonas Aeruginosa Resistance
The clinical use, safety and effectiveness of ceftolozane/tazobactam among 13 patients 3 months to 19 years of age infected with multidrug-resistant Pseudomonas aeruginosa are described. All but one patient achieved clinical cure after initial treatment. Adverse drug events attributed to treatment included transaminitis and neutropenia which occurred in 2 patients and resolved upon dose reduction.
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John S. Bradley, Jocelyn Y. Ang, Antonio Arrieta et al. · The Pediatric Infectious Disease Journal · 2018 · 40 citations