Inhibition of Endothelial PHD2 Suppresses Post-Ischemic Kidney Inflammation through Hypoxia-Inducible Factor-1 - Concepedia

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Publication | Open Access

Inhibition of Endothelial PHD2 Suppresses Post-Ischemic Kidney Inflammation through Hypoxia-Inducible Factor-1

DOI Full Paper Access

49

Citations

41

References

2020

Year

Ganeshkumar Rajendran, Michael Schonfeld, Ratnakar Tiwari, Shengping Huang, Rafael Torosyan, Timothy A. Fields, Jihwan Park, Katalin Suszták, Pinelopi P. Kapitsinou

Journal of the American Society of Nephrology

Abstract

Our findings suggest that activation of endothelial HIF-1 signaling through PHD2 inhibition may offer a novel therapeutic approach against ischemic AKI.

References

	Year	Citations

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