The synthesis of sulfonated 4<i>H</i>-3,1-benzoxazines <i>via</i> an electro-chemical radical cascade cyclization

Abstract

A new route for the synthesis of sulfonated 4H-3,1-benzoxazines has been accomplished by electrochemical radical cascade cyclizations of styrenyl amides with sulfonylhydrazines. This process demonstrates a wide substrate scope with diverse functional group compatibility under metal- and external oxidant-free conditions at ambient temperature.