Poly lactic‐co‐glycolic acid scaffold loaded with plasmid DNA encoding fibroblast growth factor‐2 promotes periodontal ligament regeneration of replanted teeth

Abstract

The PLGA/pFGF-2 scaffold promoted hPDLCs proliferation and facilitated periodontal ligament-related differentiation. The PLGA/pFGF-2 scaffold possesses excellent biological characteristics and could be used as a promising biomaterial for improving the treatment prognosis of replanted tooth.