Enterotype <i>Bacteroides</i> Is Associated with a High Risk in Patients with Diabetes: A Pilot Study

Abstract

We identified two enterotypes, <i>Bacteroides</i> and <i>Prevotella</i>, among all subjects. Our results showed that the <i>Bacteroides</i> enterotype was an independent risk factor for type 2 diabetes, which was due to increased levels of lipopolysaccharide causing decreased insulin sensitivity.<i>Bacteroides</i> and <i>Prevotella</i> enterotype. Partial correlation analysis showed that lipopolysaccharide was closely associated with diamine oxidase, tumor necrosis factor-alpha, and Gutt insulin sensitivity index after adjusting for multiple covariates. Furthermore, the level of lipopolysaccharide was found to be an independent risk factor for insulin sensitivity. <i>Bacteroides</i> and.