Acute and subchronic oral toxicity assessments of Combretum micranthum (Combretaceae) in Wistar rats

Abstract

The present study revealed that oral administration of CM extract for 28 days, at dosage up to 1000 mg/kg did not induce toxicological damage in rats. From acute toxicity study, the median lethal dose (LD₅₀) of the extract was estimated to be more than 5000 mg/kg.