Curcumin alleviates isoproterenol-induced cardiac hypertrophy and fibrosis through inhibition of autophagy and activation of mTOR. - Concepedia

Concepedia

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Curcumin alleviates isoproterenol-induced cardiac hypertrophy and fibrosis through inhibition of autophagy and activation of mTOR.

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References

2018

Year

R Liu, HB Zhang, Jiayu Yang, J-R Wang, JX Liu, Chaolun Li

Abstract

Our data demonstrated that curcumin targeted mTOR/autophagy axis could attenuate cardiac hypertrophy and fibrosis in a rat model.