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Carbonyl Reductase 1 Plays a Significant Role in Converting Doxorubicin to Cardiotoxic Doxorubicinol in Mouse Liver, but the Majority of the Doxorubicinol-Forming Activity Remains Unidentified

Daniel H. Breysse, Ryan M. Boone, Cameron M. Long, Miranda Merrill, Christopher M. Schaupp, Collin C. White, Terrance J. Kavanagh, Edward E. Schmidt, Gary F. Merrill

Drug Metabolism and Disposition · 2020 · 19 citations · 28 references

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28

Congestive heart failure in patients treated with doxorubicin

Sandra M. Swain, Fredrick S. Whaley, Michael S. Ewer · Cancer · 2003 · 2.2K citations · Full text

Organelle isolation: functional mitochondria from mouse liver, muscle and cultured filroblasts

Christian Frezza, Sara Cipolat, Luca Scorrano · Nature Protocols · 2007 · 1.2K citations · Full text

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Rat liver thioredoxin and thioredoxin reductase: purification and characterization

Mikaela Luthman, Arne Holmgren · Biochemistry · 1982 · 601 citations

Doxorubicin cardiotoxicity may be caused by its metabolite, doxorubicinol.

Richard D. Olson, Phillip S. Mushlin, Dean E. Brenner et al. · Proceedings of the National Academy of Sciences · 1988 · 352 citations · Full text

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Reduction of Dehydroascorbate to Ascorbate by the Selenoenzyme Thioredoxin Reductase

James M. May, Shalu Mendiratta, Kristina E. Hill et al. · Journal of Biological Chemistry · 1997 · 343 citations · Full text