Expression of two glutamate decarboxylase genes in <i>Lactobacillus brevis</i> during gamma-aminobutyric acid production with date residue extract

Abstract

Gamma-aminobutyric acid (GABA) is produced by <i>Lactobacillus brevis</i> using date residue fermentation. In this study, the GABA production method was improved, for which <i>L. brevis</i> strain JCM 1059^T was the most efficient among the four <i>L. brevis</i> strains examined. This was presumably due to a difference in the expression level of the gene encoding glutamate decarboxylase that catalyzes GABA synthesis.<b>Abbreviation:</b> GABA: gamma-aminobutyric acid.