<i>FLNC</i> truncations cause arrhythmogenic right ventricular cardiomyopathy

Abstract

The identification of <i>FLNCtv</i> as a novel cause of ARVC in two unrelated families expands the spectrum of ARVC <i>non-desmosome</i> disease genes for this disorder. Our findings should prompt inclusion of <i>FLNC</i> genetic testing in ARVC to improve diagnostic yield and testing of at-risk relatives in ARVC.