Neuronal branching of sensory neurons is associated with BDNF‐positive eosinophils in atopic dermatitis

Abstract

Our results indicate that BDNF-positive eosinophils are also localized in close proximity with nerve fibres in AD, suggesting a functional relationship between BDNF-expressing eosinophils and neuronal projections. These observations suggest that eosinophils may have considerable impact on pruritus by supporting sensory nerve branching.