Studies in Regional Heparinization

Abstract

REGIONAL heparinization is a technic whereby heparin is infused into an artery at such a rate that the coagulation time of the blood is prolonged in the area supplied by that artery, but the clotting time in the rest of the body remains normal owing to dilution of the heparinized blood. The technic has been applied primarily after operations on an artery, such as endarteriectomy, in which there is a considerable possibility that postoperative thrombosis will result in obstruction of the vessel. This danger is particularly great when the distal arterial bed is partially obstructed by atherosclerosis. A number of . . .