The Antibacterial Efficacy and In Vivo Toxicity of Sodium Hypochlorite and Electrolyzed Oxidizing (EO) Water-Based Endodontic Irrigating Solutions

Abstract

Both NaOCl and HOCl revealed similar antibacterial efficacy (> 99.9%) against <i>Enterococcus faecalis</i> and <i>Streptococcus mutans</i>. While 1.5% NaOCl fully dissolved the Zebrafish embryos, both 0.0125% and 0.0250% HOCl showed little in vivo toxicity, affirming its potential as an alternative irrigation solution for vital pulp therapy.