The Sigma-1 Receptor at the Crossroad of Proteostasis, Neurodegeneration, and Autophagy

Sigma-1 Receptor Chaperones at the ER- Mitochondrion Interface Regulate Ca2+ Signaling and Cell Survival

Teruo Hayashi, Tsung‐Ping Su · Cell · 2007 · 1.8K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14

Autophagosomes form at ER–mitochondria contact sites

Maho Hamasaki, Nobumichi Furuta, Atsushi Matsuda et al. · Nature · 2013 · 1.7K citations

Life Sciences, Cell Biology, Molecular Biology +11

Purification, molecular cloning, and expression of the mammalian sigma1-binding site.

Markus Hanner, Fabian F. Moebius, Astrid Flandorfer et al. · Proceedings of the National Academy of Sciences · 1996 · 908 citations

Medicine, Biochemistry, Pharmacology +13

A mutation in sigma‐1 receptor causes juvenile amyotrophic lateral sclerosis

Amr Al‐Saif, Futwan Al‐Mohanna, Saeed Bohlega · Annals of Neurology · 2011 · 424 citations

Life Sciences, Genetics, Neurology +17

Mitochondria‐associated membrane collapse is a common pathomechanism in SIGMAR1‐ and SOD1‐linked ALS

Seiji Watanabe, Hristelina Ilieva, Hiromi Tamada et al. · EMBO Molecular Medicine · 2016 · 222 citations · Full text

Life Sciences, Neurology, Neuroscience +16