The Gamma Globulins and Their Clinical Significance

Paul A. M. Gross, David Gitlin, Charles A. Janeway

New England Journal of Medicine · 1959 · 40 citations · 41 references

Concepts

Abstract

(Concluded)*Clinical Uses of Gamma GlobulinThe separation of gamma globulins from human plasma for use in the prevention and treatment of infectious diseases was made possible during World War II by the procurement of large plasma pools by the American Red Cross and by the successful development of human plasma-fractionation technics. Although the gamma-globulin fraction (fraction II of Cohn) contains almost all the plasma antibodies against many bacteria and viruses, the specific antibody content of any given lot of gamma globulin depends entirely upon the particular immune antibodies present in the plasma of the donors. The concentration and variety . . .

References

41