Concepedia

Smart Nanovesicle-Mediated Immunogenic Cell Death through Tumor Microenvironment Modulation for Effective Photodynamic Immunotherapy

Weijing Yang, Fuwu Zhang, Hongzhang Deng, Lisen Lin, Sheng Wang, Fei Kang, Guocan Yu, Joseph Lau, Rui Tian, Mingru Zhang,

ACS Nano · 2019 · 252 citations · 31 references

DOI

Concepts

Abstract

T cell development. This study exploited the nanocarrier to induce ICD for the host's immunity activation. The "all-in-one" smart nanovesicles allow the design of multifunctional materials to strengthen cancer immunotherapy efficacy.

References

31

Calreticulin exposure dictates the immunogenicity of cancer cell death

Michel Obéid, Antoine Tesnière, François Ghiringhelli et al. · Nature Medicine · 2006 · 3.1K citations

, , +14

Core-shell nanoscale coordination polymers combine chemotherapy and photodynamic therapy to potentiate checkpoint blockade cancer immunotherapy

Chunbai He, Xiaopin Duan, Nining Guo et al. · Nature Communications · 2016 · 755 citations · Full text

, , +17

Low-dose X-ray radiotherapy–radiodynamic therapy via nanoscale metal–organic frameworks enhances checkpoint blockade immunotherapy

Kuangda Lu, Chunbai He, Nining Guo et al. · Nature Biomedical Engineering · 2018 · 594 citations

, , +14

Combining Nanomedicine and Immunotherapy

Yang Shi, Twan Lammers · Accounts of Chemical Research · 2019 · 456 citations · Full text

, , +14

Nano-enabled pancreas cancer immunotherapy using immunogenic cell death and reversing immunosuppression

Jianqin Lu, Xiangsheng Liu, Yu‐Pei Liao et al. · Nature Communications · 2017 · 439 citations · Full text

, , +17