Human Blastomycosis in South Africa Caused by<i>Blastomyces percursus</i>and<i>Blastomyces emzantsi</i>sp. nov., 1967 to 2014

Abstract

We reevaluated 20 cases of blastomycosis diagnosed in South Africa between 1967 and 2014, with Blastomyces dermatitidis considered to be the etiological agent, in light of newly described species and the use of more advanced technologies. In addition to histopathological and/or culture-based methods, all 20 isolates were phenotypically and genotypically characterized, including multilocus typing of five genes and whole-genome sequencing.