Low‐valent Cobalt Complexes in C–X Coupling and Related Reactions

Abstract

Economical and eco-compatible catalytic systems are essential for carbon–carbon and carbon–heteroatom bond formation involving cross-coupling reactions. Among them, cobalt-catalysed protocols allow a wide range of functional groups and offer an excellent alternative to usual catalysts such as palladium and nickel. Different cobalt-catalysed carbon–carbon bond formations have already been reported either from various stoichiometric organometallic species or by reductive cross-coupling reactions. Although several organometallic species can be used for cobalt-catalysed cross-coupling reactions, Grignard and organozinc reagents are mainly employed. However, the advantage of developing new reductive cross-couplings directly from two electrophiles avoids the preparation of stoichiometric organometallic reagents. This chapter deals with these different cobalt-catalysed cross-coupling reactions.