Concepedia

Continuous photochemical benzylic bromination using <i>in situ</i> generated Br<sub>2</sub>: process intensification towards optimal PMI and throughput

Alexander Steiner, Jason D. Williams, Óscar de Frutos, Juan A. Rincón, Carlos Mateos, C. Oliver Kappe

Green Chemistry · 2019 · 58 citations · 34 references

DOIFull text

Open access

Concepts

Abstract

Using a Br<sub>2</sub> generator in flow process intensified conditions has been developed for photochemical benzylic bromination on a kg scale.

References

34

CHEM21 selection guide of classical- and less classical-solvents

Denis Prat, A.S. Wells, John Hayler et al. · Green Chemistry · 2015 · 2.1K citations · Full text

, , +10

Using the Right Green Yardstick: Why Process Mass Intensity Is Used in the Pharmaceutical Industry To Drive More Sustainable Processes

Concepción Jiménez‐González, Celia S. Ponder, Quirinus B. Broxterman et al. · Organic Process Research & Development · 2011 · 860 citations

, , +17

The Green ChemisTREE: 20 years after taking root with the 12 principles

Hanno C. Erythropel, Julie B. Zimmerman, Tamara M. de Winter et al. · Green Chemistry · 2018 · 780 citations

, , +16

Oxidative Halogenation with “Green” Oxidants: Oxygen and Hydrogen Peroxide

Ajda Podgoršek, Marko Zupan, Jernej Iskra · Angewandte Chemie International Edition · 2009 · 420 citations

, , +6

Flow photochemistry: Old light through new windows

Jonathan P. Knowles, Luke D. Elliott, Kevin I. Booker‐Milburn · Beilstein Journal of Organic Chemistry · 2012 · 398 citations · Full text

, , +14