Optics Express · 2019 · 136 citations · 17 references
EngineeringBioengineeringBiomedical EngineeringBiomedical OpticsBiophotonicsPhotonicsImplantable Biomedical DevicesImplantable Neural DevicesNeuromodulationNeurostimulationOptoelectronic DevicesOptogeneticsDeep Ultraviolet LithographyImplantable Neural StimulationOptogenetic ImplantsOptogenetic StimulationSiliconSilicon WafersSingle-mode PropagationSingle-mode Waveguides
We present passive, visible light silicon nitride waveguides fabricated on ≈ 100 µm thick 200 mm silicon wafers using deep ultraviolet lithography. The best-case propagation losses of single-mode waveguides were ≤ 2.8 dB/cm and ≤ 1.9 dB/cm over continuous wavelength ranges of 466-550 nm and 552-648 nm, respectively. In-plane waveguide crossings and multimode interference power splitters are also demonstrated. Using this platform, we realize a proof-of-concept implantable neurophotonic probe for optogenetic stimulation of rodent brains. The probe has grating coupler emitters defined on a 4 mm long, 92 µm thick shank and operates over a wide wavelength range of 430-645 nm covering the excitation spectra of multiple opsins and fluorophores used for brain stimulation and imaging.
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