PubMed · 2017 · 24 citations · 24 references
Open access
MedicineInfectious DiseasesInternal MedicineClinical BiochemistryHepatologyImmunopathologyAcute Liver FailureBiomarkers Of Liver InjuryHepatic EncephalopathyHepatic Function TestingLiver DiseaseLiver Function TestsAcute Hepatic FailureAcute Liver Failure ManagementAcute Liver Injury BiomarkersClinical Value AssessmentPositive Predictive ValueTotal Serum Bilirubin
BACKGROUND: Procalcitonin (PCT) is a known diagnostic marker of bacterial infection. There are no previous reports of PCT concerning acute liver failure (ALF). We evaluated the clinical value of serum PCT levels in patients with ALF. METHODS: Forty-four patients with acute hepatitis (19 men and 25 women; median age, 40 years; range, 20-79 years) were retrospectively enrolled from January 2001 and June 2015. PCT levels were measured by saved serum samples obtained within 3 days after admission. ALF was defined as prothrombin time (PT) < 40% regardless of hepatic encephalopathy. RESULTS: = 0.0314), but it was not an independent prognostic factor. CONCLUSION: Serum PCT level was significantly higher in patients with ALF.
24
High serum procalcitonin concentrations in patients with sepsis and infection
M. Assicot, Claude Bohuon, D Gendrel et al. · The Lancet · 1993 · 2.2K citations · Full text
Veterinary Medicine, Infectious Diseases, Internal Medicine +12
Early indicators of prognosis in fulminant hepatic failure
John G. O'Grady, Graeme Alexander, Karen M. Hayllar et al. · Gastroenterology · 1989 · 2.1K citations
Multivariate analysis of prognostic factors in fulminant hepatitis B
Jacques Bernuau, A Goudeau, Thierry Poynard et al. · Hepatology · 1986 · 503 citations