FeCl₃ mediated dimerization of dihydropyrrolo[2,1-<i>a</i>]isoquinolines and chlorination of tetrasubstituted pyrroles

Abstract

-mediated oxidative homocoupling. A series of dimeric dihydropyrroloisoquinoline derivatives were obtained in acceptable to excellent yields (up to >99%). Attempts to expand this dimerization system to the synthesis of dimeric pyrroles failed and chlorination products were obtained in most cases instead of dimeric pyrroles.