Concepedia

Publication | Open Access

Synaptic biomarkers in CSF aid in diagnosis, correlate with cognition and predict progression in MCI and Alzheimer's disease

DOIFull Paper Access

144

Citations

39

References

2019

Year

Douglas Galasko, Mei-Fang Xiao, Desheng Xu, Denis Smirnov, David P. Salmon, Nele Dewit, Jeroen Vanbrabant, Dirk Jacobs, Hugo Vanderstichele, Eugeen Vanmechelen
Alzheimer s & Dementia Translational Research & Clinical Interventions

Abstract

CSF synaptic biomarkers, particularly NPTX2, which regulates synaptic homeostasis, relate to cognition and predict progression in AD beyond Aβ1-42 and Tau. This is relevant for prognosis and clinical trials.

References

YearCitations

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