Diagnosis Across the Spectrum of Progressive Supranuclear Palsy and Corticobasal Syndrome

Edwin Jabbari, Negin Holland, Viorica Chelban, P. Simon Jones, Ruth Lamb, Charlotte Rawlinson, Tong Guo, Alyssa Costantini, Manuela Tan, Amanda Heslegrave,

JAMA Neurology · 2019 · 168 citations · 30 references

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Abstract

These findings suggest that studies focusing on the PSP-RS subtype are likely to miss a large number of patients with underlying PSP tau pathology. Analysis of cerebrospinal fluid defined a distinct CBS-AD subtype. The PSP and CBS subtypes have distinct characteristics that may enhance their early diagnosis.

References

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