Expression of miR-133a-5p and ROCK2 in Heart in Methamphetamine-Induced Rats and Intervention of Rhynchophylline - Concepedia

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Expression of miR-133a-5p and ROCK2 in Heart in Methamphetamine-Induced Rats and Intervention of Rhynchophylline

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2019

Year

Yuting Zhou, Yingbo Lin, Zhijie Chen, Zhu Chen, Chan Li, Hancheng Li, Chuying Huo, Jinying Ou, Jing Li, Chaohua Luo,

Abstract

The active ingredient of Chinese herbal medicine rhynchophylline can effectively inhibit the formation of methamphetamine-dependent conditional place preference (CPP) effect in rats to some extent. MiR-133a-5p may participate in the cardioprotective effects of CPP rats by targeting ROCK2.