Concepedia

Parasite Infections, Allergy and Asthma: A Role for Tropomyosin in Promoting Type 2 Immune Responses

Ana Carolina A.F. Sousa-Santos, Adriana S. Moreno, Ana Beatriz R. Santos, Michelle Barbosa, Davi Casale Aragon, Valéria Soraya Farias Sales, L. Karla Arruda

International Archives of Allergy and Immunology · 2019 · 17 citations · 10 references

DOI

Abstract

Our results suggest that IgE responses to tropomyosin from A. lumbricoides may enhance reactivity to homologous allergens upon exposure by inhalation or ingestion, promoting allergic reactions and asthma, or increasing the severity of these clinical conditions.

References

10

Experimental hookworm infection: a randomized placebo‐controlled trial in asthma

Johanna Feary, Andrea Venn, Kevin Mortimer et al. · Clinical & Experimental Allergy · 2010 · 191 citations · Full text

Cross-reactive IgE antibody responses to tropomyosins from Ascaris lumbricoides and cockroach

Ana Beatriz R. Santos, Gutemberg Melo Rocha, Constance Oliver et al. · Journal of Allergy and Clinical Immunology · 2008 · 107 citations · Full text

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Allergenicity of recombinant Bla g 7, German cockroach tropomyosin

Kyoung Yong Jeong, Jongsun Lee, In Yong Lee et al. · Allergy · 2003 · 81 citations · Full text

IgE responses to <i>Ascaris</i> and mite tropomyosins are risk factors for asthma

Velky Ahumada, Elizabeth García, Rodolfo Dennis et al. · Clinical & Experimental Allergy · 2015 · 68 citations · Full text

Allergenicity of &lt;i&gt;Ascaris lumbricoides&lt;/i&gt; Tropomyosin and IgE Sensitization among Asthmatic Patients in a Tropical Environment

Nathalie Acevedo, A. Erler, Peter Briza et al. · International Archives of Allergy and Immunology · 2010 · 66 citations