Association between variants of the autophagy related gene ATG16L1 in inflammatory bowel diseases and clinical statues.

Abstract

The results showed that ATG16L1 gene rs2241879 has a significant relationship with increased risk of IBD among an Iranian population. Individuals with C allele showed a significant relationship with 1.68-fold increased risk of IBD (P=0.01; adjusted OR=1.68; 95% CI=1.13-2.50).