A gold nanoparticle-intercalated mesoporous silica-based nanozyme for the selective colorimetric detection of dopamine

Shounak Ray, Rima Biswas, Rumeli Banerjee, Papu Biswas

Nanoscale Advances · 2019 · 70 citations · 56 references

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Abstract

adsorption-desorption, FESEM, SEM-EDS particle mapping, TEM, and XPS. The peroxidase-like activity of the AuMS material was studied thoroughly, and the effect of pH and temperature was evaluated. The reproducibility of the peroxidase mimic activity and long-term stability of the AuMS catalyst were also studied. Furthermore, the AuMS catalyst was successfully utilized for the detection and quantification of dopamine, an important neurotransmitter, colorimetrically with a linear range of 10-80 μM and a limit of detection (LOD) value of 1.28 nM. The determination of dopamine concentration in commercially available dopamine hydrochloride injection showed high accuracy, good reproducibility, and high selectivity in the presence of uric acid, ascorbic acid, glucose, tryptophan, phenylalanine, and tyrosine.

References

56