Immunity · 2019 · 320 citations · 59 references
Life SciencesImmunologyPhysiologyInflammationInnate ImmunityPathophysiologyBacterial ToxinsBacterial Virulence FactorsSepsis PathophysiologyToxin-mediated PathogenesisBacterial ExotoxinsCell Surface Phosphatidylserine ExposureCoagulationCoagulation Cascade DysregulationCoagulation-associated Phosphatidylserine ExposureEndotoxin-mediated Inflammation
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Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
Jianjin Shi, Yue Zhao, Kun Wang et al. · Nature · 2015 · 6.5K citations
Assessment of Clinical Criteria for Sepsis
Christopher W. Seymour, Theodore J. Iwashyna, Frank M. Brunkhorst et al. · JAMA · 2016 · 3.8K citations · Full text
Veterinary Medicine, Infectious Diseases, Internal Medicine +17
Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling
Nobuhiko Kayagaki, Irma B. Stowe, Bettina L. Lee et al. · Nature · 2015 · 3.7K citations
Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin
Yupeng Wang, Wenqing Gao, Xuyan Shi et al. · Nature · 2017 · 3.2K citations