Sophorolipid exhibits antifungal activity by ROS mediated endoplasmic reticulum stress and mitochondrial dysfunction pathways in <i>Candida albicans</i>

Abstract

Sophorolipid induces ROS generation in <italic>C. albicans</italic> leading to mitochondrial dysfunction and ER stress followed by the release of Ca²⁺ ions (from the ER lumen) that enter mitochondria and further magnify ROS generation leading to cell death.