Publication | Closed Access
Modified diterpenoids from the tuber of <i>Icacina oliviformis</i> as protein tyrosine phosphatase 1B inhibitors
22
Citations
43
References
2019
Year
Pharmaceutical ScienceBioorganic ChemistryOrganic ChemistryChemistryHeterocycle ChemistryChemical BiologyPharmaceutical ChemistryInhibitory ActivityDerivativesBiochemistryDiversity-oriented SynthesisPharmacologyNatural Product SynthesisBiomolecular EngineeringHeterocyclicNatural SciencesModified DiterpenoidsPimarane DerivativesMedicineDrug Discovery
Two modified diterpenoids featuring a novel 4,12-dioxatetracyclo[8.6.0.0<sup>2,7</sup>.0<sup>10,14</sup>]hexadecane core, together with a 3,4-<italic>seco</italic>-pimarane, a 3,4-<italic>seco</italic>-cleistanthane, and eight pimarane derivatives were isolated from the tuber of <italic>Icacina oliviformis</italic>.
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