Case Reports in Gastrointestinal Medicine · 2019 · 11 citations · 4 references
MedicineInfectious DiseasesPathologyGastroenterologyRheumatologySepsisGastrointestinal InflammationInflammatory Bowel DiseaseLatent Tuberculosis InfectionTuberculosis CareTuberculosis DiagnosisTuberculosis Diagnostic TestingAbdominal TuberculosisCrohn Disease PathologyDifferential Diagnosis Of TuberculosisGastrointestinal TuberculosisInflammatory Bowel Disease PathologyLatent Tuberculosis ScreeningTuberculosis DiagnosticsTuberculosis Pathology
Intestinal tuberculosis (ITB) and Crohn's disease (CD) very closely resemble each other in symptomatology, imaging, appearance, and pathology. While ITB is rare in the United States, its prevalence is significantly higher in endemic areas, thus presenting a diagnostic dilemma in immigrant populations from high-risk countries. This patient was diagnosed with CD and treated with anti-TNF agents after indeterminate screening for latent tuberculosis. He was then admitted with septic shock and intestinal perforation due to disseminated tuberculosis. This case demonstrates the importance the consideration of ITB when a patient with risk factors for TB fails to respond to treatment for CD.
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Saurabh Mukewar, Shrikant Mukewar, Raghvendra Ravi et al. · Clinical and Translational Gastroenterology · 2012 · 111 citations · Full text