Science Translational Medicine · 2019 · 118 citations · 29 references
MedicineNeurosciencePharmacologyBehavioral NeuroscienceNeuropharmacologyPsychopharmacologyAddictionDopaminergic SignalingDrugs Of AbuseReward PathwaysSerotonergic PharmacologySerotonergic SignalingCalcium ImagingDopaminergic PathwaysIn Vivo ImagingMesolimbic Reward PathwayMonoaminergic PathwaysNeural Circuit MechanismsSerotonin Transporter FunctionSerotonin Transporter Pharmacology
-fenfluramine, a selective serotonin-releasing compound. By dissociating the mechanisms of MDMA's prosocial effects from its addictive properties, we provide evidence for a conserved neuronal pathway, which can be leveraged to develop novel therapeutics with limited abuse liability.
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Social reward requires coordinated activity of nucleus accumbens oxytocin and serotonin
Gül Dölen, Ayeh Darvishzadeh, Kee Wui Huang et al. · Nature · 2013 · 1.2K citations · Full text
Medicine, Neurobiology, Neuroscience +16
Circuit Architecture of VTA Dopamine Neurons Revealed by Systematic Input-Output Mapping
Kevin T. Beier, Elizabeth E. Steinberg, Katherine E. DeLoach et al. · Cell · 2015 · 1.1K citations · Full text
Gating of social reward by oxytocin in the ventral tegmental area
Lin W. Hung, Sophie Neuner, Jai S. Polepalli et al. · Science · 2017 · 606 citations · Full text