Inhibition of TRPM7 blocks MRTF/SRF-dependent transcriptional and tumorigenic activity

Atomic model of the actin filament

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Biophysical Modeling, Physics, Natural Sciences +7

Actin Dynamics Control SRF Activity by Regulation of Its Coactivator MAL

Francesc Miralles, Guido Posern, Alexia-Ileana Zaromytidou et al. · Cell · 2003 · 1.3K citations · Full text

Protein Function, Signal Transduction, Biochemistry +11

LTRPC7 is a Mg·ATP-regulated divalent cation channel required for cell viability

Monica J. S. Nadler, Meredith C. Hermosura, Kazunori Inabe et al. · Nature · 2001 · 923 citations

Signal Transduction, Molecular Physiology, Biochemistry +12

Gene essentiality and synthetic lethality in haploid human cells

Vincent A. Blomen, Peter Májek, Lucas T. Jae et al. · Science · 2015 · 907 citations

Regulation of Vertebrate Cellular Mg2+ Homeostasis by TRPM7

Carsten Schmitz, Anne‐Laure Perraud, Catherine O. Johnson et al. · Cell · 2003 · 718 citations · Full text

Signal Transduction, Molecular Physiology, Signaling Pathway +6