Nickel‐Catalyzed Electrochemical Reductive Relay Cross‐Coupling of Alkyl Halides to Aryl Halides

Ke‐Jin Jiao, Dong Liu, Hong‐Xing Ma, Hui Qiu, Ping Fang, Tian‐Sheng Mei

Angewandte Chemie International Edition · 2019 · 216 citations · 72 references

Concepts

Abstract

A highly regioselective Ni-catalyzed electrochemical reductive relay cross-coupling between an aryl halide and an alkyl halide has been developed in an undivided cell. Various functional groups are tolerated under these mild reaction conditions, which provides an alternative approach for the synthesis of 1,1-diarylalkanes.

References

72