Angewandte Chemie International Edition · 2019 · 216 citations · 72 references
Natural SciencesChemistryCatalysisElectrochemistryOrganic ChemistryCross-coupling ReactionsElectrochemical SynthesisHeterocycle SynthesisHeterocyclic ChemistryAryl Halide CouplingCross-coupling CatalysisMild Reaction ConditionsNickel CatalysisNickel CatalystsNickel-catalyzed Cross-couplingReductive Cross-couplingUndivided Cells
A highly regioselective Ni-catalyzed electrochemical reductive relay cross-coupling between an aryl halide and an alkyl halide has been developed in an undivided cell. Various functional groups are tolerated under these mild reaction conditions, which provides an alternative approach for the synthesis of 1,1-diarylalkanes.
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Reductive Cross‐Coupling Reactions between Two Electrophiles
Christiane E. I. Knappke, Sabine Grupe, Dominik Gärtner et al. · Chemistry - A European Journal · 2014 · 750 citations · Full text