Theranostics · 2019 · 132 citations · 49 references
Veterinary MedicineImmunologyPharmacologyCell SignalingInflammationSignal TransductionCardiovascular DiseaseCoronary Artery DiseaseEndothelial ActivationEndothelial DysfunctionInflammatory MediatorsInflammatory SignalingAtherosclerosis Molecular MechanismsAtherosclerosis-associated MacrophagesLipid Profile ChangesLipid Profile EffectsLow-density Lipoprotein ParticlesLow-density Lipoprotein UptakeMonocyte AdhesionMonocyte Biology
: Our study demonstrate that formononetin can substantially attenuate the development of atherosclerosis via regulation of interplay between KLF4 and SRA, which suggests the formononetin might be a novel therapeutic approach for inhibition of atherosclerosis.
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