Inhibition of neutrophil adherence improves postischemic ventricular performance of the neonatal heart. - Concepedia

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Inhibition of neutrophil adherence improves postischemic ventricular performance of the neonatal heart.

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References

1993

Year

Ian Wilson, A. Marc Gillinov, William E. Curtis, Joseph M. DiNatale, Ronald M. Burch, Timothy J. Gardner, D. Ewen Cameron

Abstract

These data demonstrate that inhibition of neutrophil CD11b/CD18 surface adherence receptor upregulation reduces granulocyte accumulation in myocardium after hypothermic global ischemia, reduces myocyte damage, and improves ventricular systolic function.