The clinical significance of ubiquitin carboxyl hydrolase L1 and its autoantibody in neuropsychiatric systemic lupus erythematosus. - Concepedia

Concepedia

Publication | Closed Access

The clinical significance of ubiquitin carboxyl hydrolase L1 and its autoantibody in neuropsychiatric systemic lupus erythematosus.

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2019

Year

Xue Li, Jingling Sun, Rong Mu, Yuzhou Gan, Guanying Wang, Jing He, Yi Li, Qingwen Wang, Xiaolin Sun, Zhanguo Li

Abstract

Anti-UCH-L1 is a promising CSF biomarker for NPSLE diagnosis with high specificity, and the elevated levels of CSF UCH-L1 reflect the clinical severity of NPSLE. The elevation of UCH-L1 and its autoantibody in NPSLE patients showed us novel aetiological insights on NPSLE.