An asymmetric multicatalytic reaction sequence of 2-hydroxycinnamaldehydes and enolic 1,3-dicarbonyl compounds to construct bridged bicyclic acetals

Abstract

2-Hydroxycinnamaldehydes and cyclic 1,3-dicarbonyl nucleophiles were used in an asymmetric organocatalyzed reaction sequence to construct bridged bicyclic acetals <italic>via</italic> a multicatalytic process involving iminium catalysis and anion-binding catalysis.